Lucas Donigian

Lucas Donigian

Company: Zymeworks

Job title: Senior Director Business Development & Alliance Management


Engineering IL-12 for tumor specific cytotoxicity results in enhanced therapeutic window 2:30 pm

Multiple attenuating components help to mask IL-12 off-tumor mediated cytotoxicity Tumor specific activation of IL12-Fc elicits a potent anti-tumor activity in xenograft models No dose limiting toxicity observed in cynomolgus monkeys at levels well above expected therapeutic dosesRead more

day: Day Two

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